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BMI Might Have A Significant Function In The Progression Of MS

A newly published study in the journal EBioMedicine identifies an association amid high levels of blood lipids and deteriorating of disease in MS (multiple sclerosis) individuals who are obese or overweight. The longitudinal examination was conducted by scientists at the ASRC (Advanced Science Research Center) in collaboration with clinicians at the ISMMA (Icahn School of Medicine at Mount Sinai), followed lately identified MS patients for 2 Years. The scientists discovered that people who were obese or overweight had a higher level of blood lipids known as ceramides—which put markers on the DNA of monocytes—transforming them proliferate. The monocytes are blood cells that have the ability to travel to damage nerve fibers and the brain. After 2 Years into their diagnosis, the study participants had higher levels of monocytes and ceramides also had more brain injury and more loss of motor skills.

Patrizia Casaccia—ASRC Neuroscience Initiative Director—said, “Our study found important correlations amid BMI (body mass index), ceramide levels, and disease advancement in MS patients. We discovered that obese and overweight individuals with MS had higher ceramide levels than individuals having the disease who are not obese or overweight and also than people who are obese or overweight but otherwise in fit conditions. This is important since we and others had earlier identified ceramides in the CSF (cerebrospinal fluid) near the brain of MS patients, and we pointed their increased profusion to the body’s attempts to recycle the damaged myelin.

On a similar note, recently, a study of MS patients showed 18% misdiagnosed of the disease. A new study found that almost 18% of patients were identified with MS before being referred to two foremost medical centers for treatment were actually had been misdiagnosed by the autoimmune disease. The study was led by researchers from the UCLA (University of California, Los Angeles) and the UVM (University of Vermont) and analyzed the cases of 241 individuals who had been identified by other doctors and then referred to clinics over the course of a year.

Ashley Klapper
EDITOR & AUTHOR At World Industry Insights

Ashley Klapper is engaged in writing all news related to the health domain. Her in-depth knowledge in the health sector and punctuality helps her to lead the health department at World Industry Insights effortlessly. She holds experience of almost 3 years in the field. Ashley covers all news in the health sector including the latest research, inventions, and novel technologies introduced in the field. When she is not working, Ashley loves to do classical dance practice.

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