Academy Award winner Natalie Portman is set to portray the groundbreaking scientist Rosalind Franklin in the upcoming historical film, Photograph 51. Directed by acclaimed filmmaker Tom Hooper, recognized for his work on The King’s Speech, Les Misérables, and The Danish Girl, this eagerly anticipated project brings attention to the overlooked contributions of Franklin, whose research was essential to uncovering the structure of DNA. The script, written by Anna Ziegler and based on her award-winning play, forms the core narrative of the film, which is produced by industry leaders Ben Cosgrove, Mandy Greenfield, and Tom Hooper, with financial and distribution backing from FilmNation Entertainment.
Natalie Portman’s involvement in Photograph 51 heightens anticipation for a film aiming to correct a decades-old injustice in the historical record. Franklin, a pioneering British scientist, played an indispensable role in capturing Photograph 51, the x-ray crystallography image that revealed DNA’s double-helix structure. Despite the centrality of her findings, Franklin’s name was notably absent when Watson and Crick received the Nobel Prize for the discovery, highlighting the pervasive gender bias that defined much of twentieth-century science.
Tom Hooper expressed deep personal motivation for making this film, stating,
These words reflect Hooper’s commitment to forefronting the unseen stories that have changed the trajectory of world history.

Photograph 51 dives into Franklin’s quest to decode the genetic instructions for all known life, as she navigates both her colleagues and professional rivals. The film not only unpacks the scientific race that defined an era, but also addresses the personal challenges Franklin endured as she broke ground in a male-dominated field. The initial synopsis describes her as a “wronged heroine,” the “forgotten heroine,” and
reinforcing how Franklin’s pivotal role has too often remained in the shadows. Natalie Portman’s portrayal aims to bring new nuance and depth to a woman whose legacy has always deserved brighter recognition.
As production for Photograph 51 moves forward, industry observers and fans alike await the impact this film may have on public understanding of Rosalind Franklin’s enduring legacy. By elevating her untold story with Natalie Portman in the leading role, the movie promises to ignite discussion around women’s representation in science and inspire new generations to seek out the stories of other unsung pioneers. The upcoming release could prompt wider recognition of Franklin’s place in history and deepen appreciation for the scientists whose efforts were foundational yet overlooked, changing forever how such contributions are remembered.